23 March 2022

Invitation to Tender: Understanding ethnic health inequalities in the genetic testing and diagnosis of familial hypercholesterolemia

Familial hypercholesterolemia is a disorder that is typically inherited from a parent causing high cholesterol levels.  Without treatment, it can cause early heart attacks along with a higher risk of heart disease.

With some advances in clinical practice and research, a substantial gap remains in the understanding of familial hypercholesterolemia among Black, Asian and minority ethnic individuals.  In the UK, the condition can affect up to one in 250 people but more widely there could be up to 220,000 affected individuals in Britain.

The 2019 NHS Long Term Plan set an ambitious target of finding 25% of predicted patients in England over the next five years.  Due to limited data and knowledge regarding disparities in research and care for people from Black, Asian and minority ethnic individuals, the Observatory is looking to commission an organisation to add new research insights in this area; ensure limitations around clinical, genetic and population-level studies do not continue to pose risks which hamper the understanding of familial hypercholesterolemia outcomes, and outline policy recommendations to help achieve better access, experience and outcomes for our diverse communities.

We welcome submissions from all interested organisations. Tender submissions should be made by Monday 25th April 2022.

More information can be found in the Invitation to Tender PDF document here